These highlights from ERS 2025 included risk factors for acute wheeze, effect of BMI on lung function and asthma in children.

Asthma Exacerbations highlights from ERS 2025 included gobal epidemiology, use of corticosteroids and antibiotics in management of exacerbations and adverse events during pregnancy.

A pooled analysis of three cohorts found that lean MASLD patients (<25 kg/m²) faced increased risks of liver-related events (HR 2.14), liver-related mortality (HR 2.31), all-cause mortality (HR 1.26), and CVD mortality (HR 1.22) compared to non-lean MASLD. Hepatocellular carcinoma and extrahepatic cancer risks were similar, while incident cardiovascular events were slightly lower (HR 0.89).

COPD patients recovering from sepsis are more vulnerable to viral infections at 1 year than those without sepsis, including RSV (HR 3.30), influenza (3.20), varicella-zoster virus (3.05), cytomegalovirus (2.10), and herpes simplex virus (1.94). Vaccination reduced infection risk by 24-32% for varicella-zoster virus, RSV, and influenza (HR 0.67-0.72). Findings stress the need for targeted preventive strategies.

Ocular manifestations (OM) such as uveitis, episcleritis/scleritis, or orbital inflammation remain uncommon but clinically relevant in adults with IBD. Incidence was 2.9/1000 person-years, with higher risk in Crohn’s disease (CD) than ulcerative colitis (UC). Female sex (HR 1.62) and corticosteroid use (1.62) raised risk in CD, while corticosteroids (2.17) and intestinal surgery (3.50) were key predictors in UC.

While anorexia nervosa has been linked to an increased fracture risk in women, a longitudinal study discovered that men are also considerably affected. Men had a 1.86 times higher risk of fracture hospitalization, while women had a 2.26 times higher risk vs. controls. Anorexia nervosa strongly predicted osteoporotic fractures (HR 7.50), especially of the femur, humerus, and thoracic/shoulder/pelvic bones.